Week 10.02.2025 – 16.02.2025
Monday (10 Feb)
The dynamics of many-body systems, such as gases of particles or lattices of spins, often display, at large scales of space and time, a high degree of universality. Indeed, this dynamics is usually described by a few equations, those of hydrodynamics, representing
the flows of conserved currents such as those of particles and energy. This is because other "degrees of freedom" thermalise much more quickly, and the full dynamics projects onto that of conserved currents. In fact, surprisingly, even correlations between
local observables at large separations in time, and large-scale fluctuations, can be described by hydrodynamics. This is the object of various theories of hydrodynamic fluctuations, such as macroscopic fluctuation theory (for systems where diffusion dominates),
and its ballistic counterpart (for systems where persistent currents exist). I will introduce the main ideas behind such theories, restricting to systems in one dimension of space for simplicity. I will concentrate on perhaps the simplest and newest, ballistic
macroscopic fluctuation theory, taking simple examples such as the gas of classical hard rods (hard spheres, but in one dimension) - but many concepts are general.
Wednesday (12 Feb)
Encounter-based methods provide a general probabilistic framework for modelling adsorption on the surface or interior of a target. An adsorption event occurs when the contact time with the target exceeds a random threshold. If the probability distribution of the latter is an exponential function, then one recovers the Markovian example of adsorption at a constant rate, whereas a non-exponential distribution signifies non-Markovian adsorption. In the case of a partially adsorbing target surface (interior) the contact time is given by a Brownian functional known as the boundary local time (occupation time). In this talk we provide an overview of encounter-based methods. We begin by considering simple diffusive search processes. We then present several extensions of the theory such as search processes with stochastic resetting, active run-and-tumble particles, and diffusion across semipermeable membranes. Various applications to cell biology are also described.
Thursday (13 Feb)
Growth is a crucial feature of living systems, that sets them apart from most inanimate physical systems. I will discuss how statistical physics can shed light on the properties of growing living systems. Specifically, I will show how to use statistical physics to study growth of cell colonies and how their growth is coordinated with DNA replication. I will show how similar tool can be used to predict how epidemics
spread in complex networks. Finally, I will show examples of how growth generates exotic patterns in spatially extended biological systems